One of the biggest perks of working locum tenens is the ability to practice medicine in different states — from the mountains of Colorado to the coasts of Maine. But to do that, you’ll need to understand state medical licensure and how the Interstate Medical Licensure Compact (IMLC) can help fast-track your career.
Whether you're a new grad or an experienced physician, here's what you need to know about licensing for locum work in 2025 and beyond.
Do I Need a Separate License for Each State?
Yes — to legally practice medicine in a U.S. state, you must be licensed by that state’s medical board. Fortunately, most locum staffing agencies (like Odyssey Staffing) will assist with the licensing process and even cover application fees for assignments.
However, state timelines, paperwork requirements, and costs vary significantly. That’s where the IMLC comes in.
What Is the IMLC?
The Interstate Medical Licensure Compact is an agreement between participating U.S. states that simplifies the licensing process for qualified physicians. If you hold a full, unrestricted license in one IMLC state, you can apply for a license in another IMLC state without starting from scratch.
As of 2025, the IMLC includes over 30 states and territories, with more expected to join. It’s designed to increase provider mobility, reduce wait times, and streamline cross-state locum work.
Am I Eligible for the IMLC?
To apply through the IMLC, you must:
- Have a full, unrestricted license in a participating state (called your “State of Principal License” or SPL)
- Be board-certified or have passed all USMLE or COMLEX steps
- Have no disciplinary actions or open investigations
- Use the SPL as your primary residence, place of employment, or legal residence
If you qualify, your application through the IMLC can result in multiple licenses in days or weeks — not months.
How Long Does It Take to Get a New License?
Traditional state licenses: 60–120 days is typical (but some states are much faster or slower)
IMLC licenses: Often approved in 7–21 days once your IMLC profile is complete
Your locum agency can advise on current timelines and help you prioritize states that are actively hiring in your specialty.
Tips for Managing Multiple Licenses
- Keep a spreadsheet of license numbers, expiration dates, and renewal deadlines
- Renew your DEA registration or transfer it between states as needed
- Know that some states require fingerprinting or notarized forms — start early
- Always list any license (even expired) on your CV and credentialing forms
- Work with an agency that tracks and manages licensing for you
What If I'm a CRNA, PA, or NP?
Unfortunately, the IMLC currently applies only to MDs and DOs. However, some states offer expedited licensure or accept compact licenses for nurses (eNLC) and physician assistants under separate compacts or streamlined programs.
Odyssey Staffing supports licensing for all provider types and can walk you through the best path for your role and target states.
Best States for Fast Licensing
If you're looking to get started quickly, here are a few states known for fast processing (as of 2025):
- Wisconsin (IMLC participant, 2-week turnaround)
- Texas (efficient for in-state providers)
- Missouri (IMLC + responsive medical board)
- Montana (great for rural locums with quick licensing)
- Alaska (fast-track programs for urgent needs)
Your recruiter can provide updated timelines and help you focus on states with the highest demand for your specialty.
Conclusion
State licensure doesn’t have to be a roadblock — with the right support and planning, it can open doors to exciting locum tenens opportunities nationwide. The IMLC is a game-changer for mobility and speed, and many locum agencies will handle the logistics and costs on your behalf.
If you're ready to expand your reach, get licensed strategically, and take advantage of cross-state assignments, understanding the licensing process is your first step.

